Protein Modification Reagents
Medchemexpress LLC Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) | 2360920-01-8 | C55H94N10O31 | 5 MG
Mal-EGGGG-PEG8-amide-bis(deoxyglucitol) is a cleavable ADC linker. This product is for research use only and has not been fully validated for medical applications.
- Target: ADC linker
- Pathway: Antibody-drug conjugate/ADC related
- Storage at -20°C, protected from light, and under nitrogen
- In solvent storage at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen
- Soluble in H₂O at 100 mg/mL (71.87 mM) with ultrasonic assistance
Medchemexpress LLC Pomalidomide-5'-PEG5-C2-COOH | 2412056-50-7 | 98.1% | 565.57 | 25 MG
Pomalidomide-5'-PEG5-C2-COOH is an active compound used for the research of various biochemicals. It is designed for research purposes only.
- Active compound for biochemical studies
- Targeted as a drug derivative
- Appears as an oil, green to dark green in color
- Molecular weight: 565.57
- Purity: 98.1%
- Store at -20°C, protected from light and under nitrogen
Medchemexpress LLC Azide-PEG-azide | 95.0% | 50 MG
Azide-PEG-azide is a PEG-based PROTAC linker used in the synthesis of PROTACs. It acts as a click chemistry reagent, featuring an Azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 2055042-62-9 | N-(Amino-PEG3)-N-bis(PEG3-t-butyl ester) | Broadpharm | MFCD30182037 | 712.919 | C34H68N2O13 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(=O)OC(C)(C)C | 500mg | 550804310
N-(Amino-PEG3)-N-bis(PEG3-t-butyl ester) | Broadpharm | 2055042-62-9 | MFCD30182037 | 712.919 | C34H68N2O13 | 97.000 | CC(C)(C)OC(=O)CCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(=O)OC(C)(C)C | 500mg | 550804310
Kyfora Bio Polyethylene glycol MW 400
Polyethylene glycol (PEG) is a water-soluble biologically inert polymer that has a number of biological and pharmaceutical applications Specifically PEG400 can be used as an excipient in pharmaceutical products or as a coating on nanoparticles to prevent opsonization in vivo It can also be used for purification of plasmid DNA The polymer chains are hydroxyl terminated at both ends
Medchemexpress LLC DBCO-PEG12-maleimide | 00-00-0 | 98.0% | C52H74N4O17 | 10MG
DBCO-PEG12-maleimide is a PEG12-based bifunctional linker for bioconjugation and PROTAC synthesis. It combines a dibenzocyclooctyne (DBCO) moiety for strain-promoted alkyne-azide cycloaddition and a maleimide group for selective thiol conjugation, providing a flexible, hydrophilic spacer for assembling complex conjugates. Supplied as a high-purity reagent for research use.
- Enables copper-free click chemistry via strain-promoted alkyne-azide cycloaddition.
- Provides thiol-selective conjugation through a maleimide reactive handle.
- Offers a PEG12 spacer to increase solubility and reduce steric hindrance.
- High purity suitable for research applications.
- Stable when stored under recommended conditions.
Medchemexpress LLC DBCO-PEG4-C2-acid | 1537170-85-6 | 99.2% | 250 MG
DBCO-PEG4-C2-acid is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent with a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. PROTACs, which contain two different ligands connected by a linker (one for an E3 ubiquitin ligase and one for the target protein), utilize the intracellular ubiquitin-proteasome system for selective target protein degradation.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains a DBCO group
- Facilitates strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with azide groups in molecules
eMolecules Combi-Blocks DBCO-PEG4-NHS ester 250mg 303348571 QJ-9191 95 000 1427004-19-0 MFCD26793797 649 697 C34H39N3O10
Combi-Blocks DBCO-PEG4-NHS ester 250mg 303348571 QJ-9191 95 000 1427004-19-0 MFCD26793797 649 697 C34H39N3O10
![Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-1000]-fluorescein | 1000788-53-3 | 95.0% | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000281136.png-250.jpg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-1000]-fluorescein | 1000788-53-3 | 95.0% | 25 MG
DSPE-PEG-FITC (MW 1000) is a fluorescein-labeled PEGylated phospholipid designed for incorporation into liposomes, micelles, and nanoparticle formulations for fluorescent tracking. The construct combines a distearoyl phosphoethanolamine lipid anchor with a poly(ethylene glycol) spacer terminating in fluorescein; typical purity is 95% (CAS 1000788-53-3).
- Enables fluorescent labeling of liposomes and nanoparticles for imaging and tracking.
- Incorporates stably into lipid bilayers via a distearoyl phosphoethanolamine anchor.
- Poly(ethylene glycol) spacer reduces nonspecific interactions and improves circulation.
- Fluorescein provides bright green fluorescence compatible with microscopy and flow cytometry.
- Supplied in research-scale quantities suitable for formulation and analytical work.
eMolecules 872340-65-3 | Amino-PEG20-t-butyl ester | Broadpharm | MFCD21363262 | 1026.262 | C47H95NO22 | 90.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 500mg | 550804579
Amino-PEG20-t-butyl ester | Broadpharm | 872340-65-3 | MFCD21363262 | 1026.262 | C47H95NO22 | 90.000 | CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN | 500mg | 550804579
eMolecules 160743-62-4 | DMG-PEG 2000 | Broadpharm614.949 | C36H70O7 | 98.000 | CCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCC | 5g | 627958425
DMG-PEG 2000 | Broadpharm | 160743-62-4614.949 | C36H70O7 | 98.000 | CCCCCCCCCCCCCC(=O)OCC(COCCOCCOC)OC(=O)CCCCCCCCCCCCC | 5g | 627958425
Hampton Research HR2-139/PEG/Ion HT - 1 ml, Deep Well block format
HR2-139/PEG/Ion HT - 1 ml, Deep Well block format. Please note items from this supplier are non-returnable.
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG20-CH2CH2COOH | 25 g | CAS 1952360-93-8 | MDL MFCD21363316
Fmoc-NH-PEG20-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 25 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 1952360-93-8
- MDL: MFCD21363316
- InChIKey: YIKBHNBKAGGRHQ-UHFFFAOYSA-N
- Molecular Weight: 1192.397
- Molecular Formula: C58H97NO24
- Purity: ≥95%
- Container Type: 125 mL HDPE
- Pack Size: 25 g
- Net Weight: 25 g
- Gross Weight: 54.3 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64-henicosaoxa-4-azaheptahexacontan-67-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O)O