Protein Modification Reagents
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG4-CH2COOH | 5 g | CAS 437655-95-3 | MDL MFCD26142981
Fmoc-NH-PEG4-CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 437655-95-3
- MDL: MFCD26142981
- InChIKey: XPNLDOFYRFOXLR-UHFFFAOYSA-N
- Molecular Weight: 473.522
- Molecular Formula: C25H31NO8
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azaoctadecan-18-oic acid
- SMILES: O=C(COCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
eMolecules Propargyl-PEG3-triethoxysilane | 2250216-92-1 | | 1g
Broadpharm | Propargyl-PEG3-triethoxysilane | 1g | 433947070 | BP-24134 | 98.000 | 2250216-92-1 | | 419.590 | C19H37NO7Si
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Medchemexpress LLC Azido-PEG20-alcohol | 1637297-21-2 | C40H81N3O20 | 25 MG
Azido-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is a click chemistry reagent containing an Azide group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker for PROTAC synthesis.
- Click chemistry reagent containing an Azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
Medchemexpress LLC m-PEG12-Thiol | 2413368-61-1 | 95.0% | C25H52O12S | 100 MG
m-PEG12-Thiol is a PEG-based PROTAC linker, pivotal for synthesizing PROTACs. These bifunctional molecules are engineered to induce the degradation of specific target proteins within cells.
- Composed of two distinct ligands connected by a linker
- One ligand recruits an E3 ubiquitin ligase
- The other ligand binds to the target protein for degradation
- Utilizes the cell's ubiquitin-proteasome system
- Enables selective degradation of target proteins
Medchemexpress LLC 2,5,8,11-Tetraoxatridecane, 13-azido- | 606130-90-9 | 98.0% | C9H19N3O4 | 50 MG
2,5,8,11-Tetraoxatridecane, 13-azido- is a chemical compound with a molecular weight of 233.26. It appears as a colorless to light yellow liquid and is intended for research use only. This product has been tested and complies with the given specifications.
- Colorless to light yellow liquid appearance
- Molecular weight of 233.26
- Suitable for research applications
- Storage in pure form at -20°C for 3 years
- Storage in solvent at -80°C for 6 months
- Storage in solvent at -20°C for 1 month
Medchemexpress LLC Biotin-PEG4-TFP ester | 2985664-57-9 | 97.8% | C27H37F4N3O8S | 100 MG
Biotin-PEG4-TFP ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Contains two different ligands connected by a linker
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins
Medchemexpress LLC Hydroxy-PEG4-CH2COOH | 70678-95-4 | 97.0% | C10H20O7 | 100 MG
Hydroxy-PEG4-CH2COOH is a PEG-based PROTAC linker essential for the synthesis of PROTACs. These molecules are designed with two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other binding to a specific target protein. This design enables the selective degradation of target proteins by harnessing the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Essential for PROTAC synthesis
- Features two distinct ligands connected by a linker
- Targets an E3 ubiquitin ligase
- Binds to a specific target protein
- Enables selective degradation of target proteins
- Utilizes the ubiquitin-proteasome system
Medchemexpress LLC M-PEG4-hydrazide | 1449390-68-4 | >98% | C10H22N2O5 | 50 MG
m-PEG4-Hydrazide is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs.
- PROTACs are designed to contain two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest.
- PROTACs function by leveraging the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
Medchemexpress LLC Dbco-peg2-acid | 2304558-25-4 | ≥95.0% | C26H28N2O6 | 100 MG
DBCO-PEG2-acid is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It functions as a click chemistry reagent, incorporating a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules that contain Azide groups. PROTACs themselves are composed of two distinct ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to the target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based PROTAC linker.
- Utilized in the synthesis of PROTACs.
- Click chemistry reagent.
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups.
- PROTACs degrade target proteins via the ubiquitin-proteasome system.
Medchemexpress LLC Nhpi-peg4-c2-nhs ester | 1415328-95-8 | MFCD28155511 | 98.9% | 508.48 g/mol | C23H28N2O11 | 1 G
NHPI-PEG4-C2-NHS ester is a PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is supplied for research use and has a molecular weight of 508.48 g/mol and formula C23H28N2O11. Store the pure material at -20°C; observe low-temperature storage for solutions.
Medchemexpress LLC m-PEG20-alcohol 1g
m-PEG20-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
![eMolecules Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502477062.JPG-250.jpg)
eMolecules Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6
Broadpharm / DBCO-PEG2-PFP ester / 100mg / 448298236 / BP-24326 / 98.000 / 2304558-23-2 / [null] / 630.568 / C32H27F5N2O6
Medchemexpress LLC Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane | 1421933-29-0 | 97.0% | C36H66N4O14 | 100 MG
Azido-PEG4-Amido-tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent due to its Azide group. This enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with Alkyne-containing molecules and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with compounds containing DBCO or BCN groups. PROTACs leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Features an Azide group
- Enables CuAAc and SPAAC reactions
- Supports PROTACs in degrading target proteins
eMolecules AA Blocks LLC Fmoc-N-amido-PEG4-acid 100mg 410171201 AA0038KJ 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
AA Blocks LLC Fmoc-N-amido-PEG4-acid 100mg 410171201 AA0038KJ 0 000 557756-85-1 MFCD06656472 487 549 C26H33NO8
eMolecules Maleimide-NH-PEG8-CH2CH2COONHS Ester | 756525-93-6 | 1G | Purity: 98%
Broadpharm | Maleimide-NH-PEG8-CH2CH2COONHS Ester | 1G | 756525-93-6 | MFCD21648521 | MW:63.546
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